Formulation Development of Generic Omeprazole 20 mg Enteric Coated Tablets
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چکیده
منابع مشابه
Formulation Development of Generic Omeprazole 20 mg Enteric Coated Tablets
Omeprazole is a potent proton pump inhibitor with powerful inhibition of secretion of gastric juice. Oral site-specific drug delivery systems have recently attracted a great interest for the local treatment of bowel disease and for improving systemic absorption of drugs which are unstable in the stomach. However, microenvironment in the gastrointestinal tract and varying absorption mechanisms c...
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s: Pantoprazole 5-(difluoromethoxy)2-[(3,4-dimethoxypyridin-2-yl) methylsulfinyl]3H-benzoimidazole is a proton pump inhibitor belongs to group of benzimidazole . This compound inhabits gastric acid formation and there by it is very efficient for the treatment of gastric and duodenum ulcers. In aqueous media more acidic than pH 4 it suffers a practically complete decomposition within a period sh...
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Omeprazole, a substituted benzimidazole, is a specific and noncompetitive inhibitor of the enzyme H/K-ATPase, known as the gastric proton pump. It is unstable in conditions of low pH and must be protected from the effects of gastric acid when given orally; thus, it is administered in the form of enteric-coated dosage/arms. In this present study, various coating solutions were prepared in differ...
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Divalproex sodium Chemically it is designated as sodium hydrogen bis(2-propylpentanoate) is a stable co-ordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship and formed during the partial neutralization of valproic acid with 0.5 equivalent of sodium hydroxide. Divalproex sodium is an anticonvulsant drug. Increase level of gama-amino butyric acid in brai...
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ژورنال
عنوان ژورنال: Pharmacology & Pharmacy
سال: 2015
ISSN: 2157-9423,2157-9431
DOI: 10.4236/pp.2015.67031